Senior Scientific Director, Medical Affairs

February 19

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Orthogon Therapeutics

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Orthogon Therapeutics is a biotechnology company pioneering groundbreaking antiviral therapies specifically targeting polyomaviruses, which are among the most common viral infections affecting transplant patients. The company utilizes advanced drug discovery techniques, including machine learning and artificial intelligence, to develop innovative, orally administrable drugs aimed at treating severe clinical complications arising from these viruses and their reactivation in immune-suppressed individuals, such as kidney transplant patients. Orthogon Therapeutics is dedicated to expanding its research to additional therapeutic areas involving polyomaviruses, leveraging its unique drug development capabilities.

Drug Discovery & Development • Structure Based Drug Design • Life Sciences Research • Biotech/Pharma

2 - 10 employees

🧬 Biotechnology

⚕️ Healthcare Insurance

💊 Pharmaceuticals

💰 $8M Series B on 2021-11

📋 Description

• Are you ready to make a meaningful impact in breast cancer treatment? As a Scientific Director, Medical Affairs, you’ll be a key expert supporting the Medical Affairs team, driving scientific education, and shaping the strategy for RLY-2608, the company’s lead asset in breast cancer. • Develop and maintain scientific resources to support impactful medical education and MSL engagements. • Serve as a subject matter expert, keeping the team up to date on treatment landscapes, competitive intelligence, and evolving science. • Lead internal training to ensure the Medical Affairs team is well-versed in the product, disease area, and latest research. • Drive digital medical education initiatives, working with vendors to execute aligned strategies. • Shape the scientific narrative, collaborating cross-functionally to develop messaging on disease state, MOA, and molecular diagnostics. • Represent Medical Affairs in cross-functional teams, providing strategic and operational insights. • Lead insight collection initiatives, ensuring external perspectives help guide internal strategy. • Ensure compliance with regulatory and ethical guidelines in all scientific interactions. • Mentor and help build a high-performing Medical Affairs team to support the organization’s evolving needs. • Travel up to 25% for congresses, HCP meetings, and internal collaborations.

🎯 Requirements

• Advanced degree preferred (PharmD, PhD, MD), though experienced professionals with MSc, NP, PA, or RPh backgrounds will be considered. • 5+ years in biotech/pharma, with solid tumor oncology (breast cancer preferred) experience. • Strong expertise in clinical research, medical strategy, and evidence generation. • Deep understanding of oncology treatment guidelines, regulatory frameworks, and scientific exchange best practices. • Excellent communication skills—comfortable engaging KOLs, HCPs, researchers, and internal stakeholders. • Proven ability to lead projects, collaborate cross-functionally, and drive results. • Passion for innovation in Medical Affairs and the ability to anticipate trends that shape future strategy. • Willingness to be hands-on and adapt in a dynamic, fast-paced biotech environment.