Kyverna Therapeutics
Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company focused on developing cell therapies for patients suffering from autoimmune diseases. The company is pioneering CAR T-cell therapies, leveraging the transformational power of T cells to potentially provide sustained, treatment-free remission for autoimmune conditions. Kyverna's lead CAR T-cell therapy candidate, KYV-101, is advancing through clinical trials targeting various autoimmune diseases, including multiple sclerosis, myasthenia gravis, systemic sclerosis, and lupus nephritis. Their pipeline features innovative chimeric antigen receptor (CAR) T-cell therapies in both autologous and allogeneic formats aimed at B cell-driven autoimmune diseases.
cell therapy • autoimmune • lupus
Director, Biostatistics
January 17
Kyverna Therapeutics
Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company focused on developing cell therapies for patients suffering from autoimmune diseases. The company is pioneering CAR T-cell therapies, leveraging the transformational power of T cells to potentially provide sustained, treatment-free remission for autoimmune conditions. Kyverna's lead CAR T-cell therapy candidate, KYV-101, is advancing through clinical trials targeting various autoimmune diseases, including multiple sclerosis, myasthenia gravis, systemic sclerosis, and lupus nephritis. Their pipeline features innovative chimeric antigen receptor (CAR) T-cell therapies in both autologous and allogeneic formats aimed at B cell-driven autoimmune diseases.
cell therapy • autoimmune • lupus
📋 Description
• Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company focused on developing cell therapies for patients suffering from autoimmune diseases. • This position will help build and lead the Biostatistical group at Kyverna Therapeutics. • Working with the stats programming, clinical data management, other functional stake holders, and CROs, this position will support and oversight a variety of clinical studies. • Also responsible for planning, monitoring, organizing and reviewing activities of biostatisticians work on the studies, ensuring individual study, the overall program and integrated analyses are delivered on time, on budget with rigor and quality.
🎯 Requirements
• Ph.D. degree in Biostatistics, Statistics, or related field • At least 8 years’ experience, responsible for biostatistics in clinical trials across different therapeutic indications with in depth experience in interaction with regulatory agencies, preferable in immunology and neurology. Successful submission a big plus • Extensive experience collaborating with scientific teams to design robust and complex clinical trials with proven success in accelerated approval • Proficiency in using statistical software such as R, SAS for data analysis and modeling. Familiar with a variety of power calculation settings. Hands on experience currently on generating TFLs • Familiarity with complex and novel statistical methods that apply to applicable clinical trials, such as adaptive Bayesian design, counterfactual design in RWD • Excellent written and verbal communication skills • Ability to work cross-functionally in a fast-paced, collaborative environment • Strong attention to detail
🏖️ Benefits
• Bonus eligibility • Benefits • Participation in Company’s stock option plan
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